Difference between revisions of "FolE"
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* '''Locus tag:''' BSU22780 | * '''Locus tag:''' BSU22780 | ||
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===Phenotypes of a mutant === | ===Phenotypes of a mutant === |
Revision as of 10:19, 28 January 2012
- Description: GTP cyclohydrolase I
Gene name | folE |
Synonyms | mtrA |
Essential | no |
Product | GTP cyclohydrolase IA |
Function | biosynthesis of folate |
Metabolic function and regulation of this protein in SubtiPathways: Phe, Tyr, Trp, Folate | |
MW, pI | 21 kDa, 6.335 |
Gene length, protein length | 570 bp, 190 aa |
Immediate neighbours | mtrB, hbs |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU22780
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate (according to Swiss-Prot)
- Protein family: citrate synthase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s): zinc-dependent enzyme PubMed
- Effectors of protein activity:
Database entries
- UniProt: P19465
- KEGG entry: [3]
- E.C. number: 3.5.4.16
Additional information
Expression and regulation
- Regulation: constitutive PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References