SapB

• Description: a specific mutant activates alkaline phosphatase during sporulation independently of SigF and SigE
  
  

Gene name	sapB
Synonyms
Essential	no
Product	unknown
Function	unknown
MW, pI	25 kDa, 9.484
Gene length, protein length	696 bp, 232 aa
Immediate neighbours	yerI, opuE
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

phosphate metabolism, membrane proteins

The gene

Basic information

• Locus tag: BSU06650

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: mgtC/sapB family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: Q45514

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: sapB PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Michael B Whalen, Patrick J Piggot
Gain-of-function mutation of sapB that affects formation of alkaline phosphatase by Bacillus subtilis in sporulation conditions.
Microbiology (Reading): 1997, 143 ( Pt 2);577-583
[PubMed:9043134] [WorldCat.org] [DOI] (P p)