RsbS

• Description: anti-RsbT, part of the stressosome
  
  

Gene name	rsbS
Synonyms	ycxS
Essential	no
Product	anti-RsbT
Function	control of SigB activity
Interactions involving this protein in SubtInteract: RsbS
Metabolic function and regulation of this protein in SubtiPathways: Stress
MW, pI	13 kDa, 4.14
Gene length, protein length	363 bp, 121 aa
Immediate neighbours	rsbR, rsbT
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

sigma factors and their control, phosphoproteins

The gene

Basic information

• Locus tag: BSU04680

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Additional information

• A mutation was found in this gene after evolution under relaxed selection for sporulation PubMed

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylation on Ser-59 PubMed, dephosphorylation by RsbX PubMed

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • RsbS-RsbT PubMed
  • RsbS-RsbU
  • RsbX-RsbS PubMed
  • RsbR-RsbS
  • component of the stressosome

• Localization:

Database entries

• Structure: 3VY9 (complete stressosome)

• UniProt: P42410

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: rsbR-rsbS-rsbT-rsbU-rsbV-rsbW-sigB-rsbX PubMed

• Sigma factor: SigA PubMed

• Regulation: constitutively expressed PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

• Bill Haldenwang, San Antonio, USA
• Chet Price, Davis, USA homepage
• Rick Lewis, Newcastle, UK homepage

References

Original Articles

Additional publications: PubMed