GerT

• Description: spore coat protein, involved in germination
  
  

Gene name	gerT
Synonyms	yozR
Essential	no
Product	spore coat protein
Function	germination
MW, pI	18 kDa, 6.342
Gene length, protein length	471 bp, 157 aa
Immediate neighbours	yojE, yojC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

sporulation proteins, germination, membrane proteins

This gene is a member of the following regulons

SigK regulon

The gene

Basic information

• Locus tag: BSU19490

Expression

Expression

Phenotypes of a mutant

• mutants respond poorly to multiple germinants, impaired in early stage of germination PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: eamA transporter family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot), first assembled in foci, then spread around the developing spore in a CotE-dependent manner PubMed

Database entries

• Structure:

• UniProt: Q7WY67

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: gerT (according to DBTBS)

• Sigma factor: SigK PubMed

• Regulation:
  • expressed late during sporulation in the mother cell (SigK, GerE) PubMed

• Regulatory mechanism:
  • GerE: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Caitlin C Ferguson, Amy H Camp, Richard Losick
gerT, a newly discovered germination gene under the control of the sporulation transcription factor sigmaK in Bacillus subtilis.
J Bacteriol: 2007, 189(21);7681-9
[PubMed:17720779] [WorldCat.org] [DOI] (P p)