Difference between revisions of "Pgk"
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=== Basic information === | === Basic information === | ||
− | * '''Coordinates:''' | + | * '''Coordinates:''' 3479231 - 3480412 |
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
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=== Additional information=== | === Additional information=== | ||
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=The protein= | =The protein= |
Revision as of 12:00, 13 January 2009
- Description: catalyzes the reaktion of 1,3-phosphoglycerate to 3-Phosphoglycerate by phosphorylation of ADP and the reverse reaktion
Gene name | pgk |
Synonyms | |
Essential | yes |
Product | Phosphoglycerate kinase |
Function | phosphorylation |
MW, pI | 42,0 kDa, 4.77 |
Gene length, protein length | 1182 bp, 394 amino acids |
Immediate neighbours | gapA, tpi |
Gene sequence (+200bp) | Protein sequence |
Genetic context |
Contents
The gene
Basic information
- Coordinates: 3479231 - 3480412
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate
- Protein family: phosphoglycerate kinase family
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- nucleotide binding domain (ATP) (350–353)
- 2x substrate binding domain (21–23), (59–62)
- Modification: phosphorylation PubMed,
- Cofactor(s):
- Effectors of protein activity:
- Interactions: Pgk-GapA
- Localization: Cytoplasm PubMed
Database entries
- Structure: Geobacillus stearothermophilus NCBI
- Swiss prot entry: [3]
- KEGG entry: [4]
- E.C. number: [5]
Additional information
Expression and regulation
- Sigma factor: SigA
- Additional information:
Biological materials
Labs working on this gene/protein
Your additional remarks
References
- Ludwig, H., Homuth, G., Schmalisch, M., Dyka, F. M., Hecker, M., and Stülke, J. (2001) Transcription of glycolytic genes and operons in Bacillus subtilis: evidence for the presence of multiple levels of control of the gapA operon. Mol Microbiol 41, 409-422.PubMed