Difference between revisions of "SpoIIE"
(→Extended information on the protein) |
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=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' dephosphorylation of [[SpoIIAA]] |
* '''Protein family:''' PP2C [[Protein kinases and phosphatases|phosphatase]] | * '''Protein family:''' PP2C [[Protein kinases and phosphatases|phosphatase]] | ||
| Line 89: | Line 89: | ||
** [[SpoIIE]]-[[SpoIIE]] | ** [[SpoIIE]]-[[SpoIIE]] | ||
** [[SpoIIQ]]-[[SpoIIE]] | ** [[SpoIIQ]]-[[SpoIIE]] | ||
| + | ** forms a dimer {{PubMed|22115775}} | ||
| − | * '''[[Localization]]:''' cell membrane (according to Swiss-Prot) | + | * '''[[Localization]]:''' |
| − | + | ** cell membrane (according to Swiss-Prot) | |
| + | ** localizes to the polar cell division sites where it causes [[FtsZ]] to relocate from mid-cell to form polar Z-rings | ||
=== Database entries === | === Database entries === | ||
* '''Structure:''' | * '''Structure:''' | ||
| − | + | ** [http://www.rcsb.org/pdb/explore.do?structureId=3T91 3T91] (phosphatase domain) {{PubMed|22115775}} | |
* '''UniProt:''' [http://www.uniprot.org/uniprot/P37475 P37475] | * '''UniProt:''' [http://www.uniprot.org/uniprot/P37475 P37475] | ||
| Line 140: | Line 142: | ||
=References= | =References= | ||
| − | <pubmed>7570023,7570022,12180929,9077448,9364910,10323866,8622920,12007411,16824103,10476035,10747015,10322028,15978076,9495766,14744853,9642177,15866939,8846916,1556084,1948031,9573053,18077456,11846550,9150232,15205443,1556084,15687200, 19578359 10049355 20817757 </pubmed> | + | <pubmed>7570023,7570022,12180929,9077448,9364910,10323866,8622920,12007411,16824103,10476035,10747015,10322028,15978076,9495766,14744853,9642177,15866939,8846916,1556084,1948031,9573053,18077456,11846550,9150232,15205443,1556084,15687200, 19578359 10049355 20817757 22115775 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 13:44, 28 November 2011
- Description: protein serine phosphatase, septum-associated PP2C, dephosphorylation of SpoIIAA
| Gene name | spoIIE |
| Synonyms | spoIIH, spoIIK |
| Essential | no |
| Product | protein serine phosphatase, septum-associated PP2C |
| Function | control of SigF activity required for normal formation of the asymmetric septum |
| Interactions involving this protein in SubtInteract: SpoIIE | |
| Metabolic function and regulation of this protein in SubtiPathways: Stress | |
| MW, pI | 91 kDa, 6.137 |
| Gene length, protein length | 2481 bp, 827 aa |
| Immediate neighbours | trnSL-Glu1, yabS |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
protein modification, sigma factors and their control, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU00640
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: dephosphorylation of SpoIIAA
- Protein family: PP2C phosphatase
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cell membrane (according to Swiss-Prot)
- localizes to the polar cell division sites where it causes FtsZ to relocate from mid-cell to form polar Z-rings
Database entries
- KEGG entry: [3]
- E.C. number: 3.1.3.16
Additional information
Expression and regulation
- Operon: spoIIE (DBTBS)
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Imrich Barak, Slovak Academy of Science, Bratislava, Slovakia homepage
Your additional remarks
References
