Difference between revisions of "YwqL"
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| − | * '''Description:''' | + | * '''Description:''' endonuclease V<br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || endonuclease V |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || DNA repair |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 26 kDa, 5.707 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 26 kDa, 5.707 | ||
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
| − | {{SubtiWiki category|[[DNA | + | {{SubtiWiki category|[[DNA repair/ recombination]]}} |
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| Line 46: | Line 46: | ||
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| − | + | * increased mutation rates {{PubMed|22056936}} | |
=== Database entries === | === Database entries === | ||
| Line 54: | Line 54: | ||
=== Additional information=== | === Additional information=== | ||
| − | |||
| − | |||
| Line 80: | Line 78: | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' | + | * '''[[SubtInteract|Interactions]]:''' |
| − | * '''Localization:''' cytoplasm (according to Swiss-Prot) | + | * '''[[Localization]]:''' cytoplasm (according to Swiss-Prot) |
=== Database entries === | === Database entries === | ||
| Line 103: | Line 101: | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** expressed throughout growth and staionary phase {{PubMed|22056936}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
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=References= | =References= | ||
| − | <pubmed>9353933 | + | <pubmed>9353933 22056936</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 11:31, 8 November 2011
- Description: endonuclease V
| Gene name | ywqL |
| Synonyms | |
| Essential | no |
| Product | endonuclease V |
| Function | DNA repair |
| MW, pI | 26 kDa, 5.707 |
| Gene length, protein length | 714 bp, 238 aa |
| Immediate neighbours | ywqM, ywqK |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU36170
Phenotypes of a mutant
- increased mutation rates PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Endonucleolytic cleavage at apurinic or apyrimidinic sites to products with a 5'-phosphate (according to Swiss-Prot)
- Protein family: endonuclease V family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure: 3GA2
- UniProt: P96724
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: ywqL PubMed
- Regulation:
- expressed throughout growth and staionary phase PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Karina López-Olmos, Martha P Hernández, Jorge A Contreras-Garduño, Eduardo A Robleto, Peter Setlow, Ronald E Yasbin, Mario Pedraza-Reyes
Roles of endonuclease V, uracil-DNA glycosylase, and mismatch repair in Bacillus subtilis DNA base-deamination-induced mutagenesis.
J Bacteriol: 2012, 194(2);243-52
[PubMed:22056936]
[WorldCat.org]
[DOI]
(I p)
E Presecan, I Moszer, L Boursier, H Cruz Ramos, V de la Fuente, M-F Hullo, C Lelong, S Schleich, A Sekowska, B H Song, G Villani, F Kunst, A Danchin, P Glaser
The Bacillus subtilis genome from gerBC (311 degrees) to licR (334 degrees).
Microbiology (Reading): 1997, 143 ( Pt 10);3313-3328
[PubMed:9353933]
[WorldCat.org]
[DOI]
(P p)
