PhrG

• Description: response regulator aspartate phosphatase (RapG) regulator
  
  

Gene name	phrG
Synonyms	yycL
Essential	no
Product	phosphatase (RapG) regulator
Function	control of DegU activity
Interactions involving this protein in SubtInteract: PhrG
MW, pI	4 kDa, 9.017
Gene length, protein length	114 bp, 38 aa
Immediate neighbours	rapG, rocF
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

transcription factors and their control, quorum sensing, short peptides

This gene is a member of the following regulons

CcpA regulon, RghR regulon, SigH regulon

The gene

Basic information

• Locus tag: BSU40310

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: binds to RapG, this results in the inability of RapG to interact with DegU PubMed

• Protein family: phr family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • PhrG-RapG PubMed

• Localization:

Database entries

• Structure:

• UniProt: O32295

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: rapG-phrG PubMed

• Sigma factor: SigA PubMed, SigH PubMed

• Regulation:
  • repressed by SinR PubMed
  • repressed by RghR PubMed
  • repressed by glucose (4.8-fold) (CcpA) PubMed

• Regulatory mechanism:
  • SinR: transcription repression PubMed
  • RghR: transcription repression PubMed
  • CcpA: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: