Difference between revisions of "LytA"
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 306 bp, 102 aa | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 306 bp, 102 aa | ||
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| − | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[lytB]]'', ''[[ | + | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[lytB]]'', ''[[tagU]]'' |
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB15581]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' | |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB15581]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' | ||
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= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| − | |||
{{SubtiWiki regulon|[[SigD regulon]]}}, | {{SubtiWiki regulon|[[SigD regulon]]}}, | ||
{{SubtiWiki regulon|[[SlrR regulon]]}}, | {{SubtiWiki regulon|[[SlrR regulon]]}}, | ||
| Line 56: | Line 55: | ||
=== Additional information=== | === Additional information=== | ||
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| − | |||
| Line 107: | Line 104: | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | |||
** [[SlrR]] (in complex with [[SinR]]: transcription repression {{PubMed|20351052}} | ** [[SlrR]] (in complex with [[SinR]]: transcription repression {{PubMed|20351052}} | ||
** [[YvrHb]]: transcription repression {{PubMed|16306698}} | ** [[YvrHb]]: transcription repression {{PubMed|16306698}} | ||
Revision as of 10:18, 30 October 2011
- Description: secretion of major autolysin LytC
| Gene name | lytA |
| Synonyms | lppX |
| Essential | no |
| Product | secretion of major autolysin LytC |
| Function | autolysis |
| MW, pI | 11 kDa, 4.061 |
| Gene length, protein length | 306 bp, 102 aa |
| Immediate neighbours | lytB, tagU |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
cell wall degradation/ turnover, membrane proteins
This gene is a member of the following regulons
SigD regulon, SlrR regulon, YvrHb regulon
The gene
Basic information
- Locus tag: BSU35640
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: Q02112
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Yunrong Chai, Thomas Norman, Roberto Kolter, Richard Losick
An epigenetic switch governing daughter cell separation in Bacillus subtilis.
Genes Dev: 2010, 24(8);754-65
[PubMed:20351052]
[WorldCat.org]
[DOI]
(I p)
Masakuni Serizawa, Keisuke Kodama, Hiroki Yamamoto, Kazuo Kobayashi, Naotake Ogasawara, Junichi Sekiguchi
Functional analysis of the YvrGHb two-component system of Bacillus subtilis: identification of the regulated genes by DNA microarray and northern blot analyses.
Biosci Biotechnol Biochem: 2005, 69(11);2155-69
[PubMed:16306698]
[WorldCat.org]
[DOI]
(P p)
P Margot, V Lazarevic, D Karamata
Effect of the SinR protein on the expression of the Bacillus subtilis 168 lytABC operon.
Microb Drug Resist: 1996, 2(1);119-21
[PubMed:9158733]
[WorldCat.org]
[DOI]
(P p)
V Lazarevic, P Margot, B Soldo, D Karamata
Sequencing and analysis of the Bacillus subtilis lytRABC divergon: a regulatory unit encompassing the structural genes of the N-acetylmuramoyl-L-alanine amidase and its modifier.
J Gen Microbiol: 1992, 138(9);1949-61
[PubMed:1357079]
[WorldCat.org]
[DOI]
(P p)
