Difference between revisions of "HtrA"

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(References)
(Extended information on the protein)
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:'''
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* '''[[SubtInteract|Interactions]]:'''
  
* '''Localization:''' cell membrane (according to Swiss-Prot)extracellular (signal peptide) [http://www.ncbi.nlm.nih.gov/pubmed/18957862 PubMed]
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* '''[[Localization]]:'''  
 +
** cell membrane (according to Swiss-Prot)
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** extracellular (signal peptide) [http://www.ncbi.nlm.nih.gov/pubmed/18957862 PubMed]
  
 
=== Database entries ===
 
=== Database entries ===

Revision as of 12:34, 10 August 2011

  • Description: serine protease Do

Gene name htrA
Synonyms ykdA
Essential no
Product serine protease Do
Function probably involved in processing, maturation,
or secretion of extracellular enzymes
Metabolic function and regulation of this protein in SubtiPathways:
Stress, Protein secretion
MW, pI 47 kDa, 4.699
Gene length, protein length 1347 bp, 449 aa
Immediate neighbours ykcC, proG
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
HtrA context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

proteolysis, heat shock proteins

This gene is a member of the following regulons

CssR regulon

The gene

Basic information

  • Locus tag: BSU12900

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: PDZ (DHR) domain (according to Swiss-Prot)
  • Paralogous protein(s): YyxA

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:
    • cell membrane (according to Swiss-Prot)
    • extracellular (signal peptide) PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: htrA (according to DBTBS)
  • Regulation:
    • expressed under conditions of secretion stress (CssR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References