YqaH

• Description: unknown, skin element
  
  

Gene name	yqaH
Synonyms
Essential	no
Product	unknown
Function	unknown
Interactions involving this protein in SubtInteract: YqaH
MW, pI	9 kDa, 5.694
Gene length, protein length	255 bp, 85 aa
Immediate neighbours	yqaI, yqaG
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

Skin element

This gene is a member of the following regulons

SknR regulon

The gene

Basic information

• Locus tag: BSU26310

Phenotypes of a mutant

• overexpression of YqaH causes cell filamentation and abnormal chromosome segregation, suggesting that overproduction of these proteins inhibits DNA replication, perhaps due to the interaction with DnaA PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: YqaH-DnaA PubMed

• Localization: Cytoplasm (Homogeneous) PubMed

Database entries

• Structure:

• UniProt: P45905

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yqaF-yqdA-yqaG-yqaH-yqaI-yqaJ-yqaK-yqaL-yqaM-yqaN PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • not expressed during normal growth (SknR) PubMed

• Regulatory mechanism:
  • SknR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Tatsu Kimura, Yukie Amaya, Kazuo Kobayashi, Naotake Ogasawara, Tsutomu Sato
Repression of sigK intervening (skin) element gene expression by the CI-like protein SknR and effect of SknR depletion on growth of Bacillus subtilis cells.
J Bacteriol: 2010, 192(23);6209-16
[PubMed:20889742] [WorldCat.org] [DOI] (I p)

Jean-Christophe Meile, Ling Juan Wu, S Dusko Ehrlich, Jeff Errington, Philippe Noirot
Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory.
Proteomics: 2006, 6(7);2135-46
[PubMed:16479537] [WorldCat.org] [DOI] (P p)

Marie-Françoise Noirot-Gros, Etienne Dervyn, Ling Juan Wu, Peggy Mervelet, Jeffery Errington, S Dusko Ehrlich, Philippe Noirot
An expanded view of bacterial DNA replication.
Proc Natl Acad Sci U S A: 2002, 99(12);8342-7
[PubMed:12060778] [WorldCat.org] [DOI] (P p)