Difference between revisions of "SscA"

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* '''Description:''' possible toxin <br/><br/>
+
* '''Description:''' small spore protein <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''yhzE''
+
|''sscA''
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
+
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yhzE ''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unkown
+
|style="background:#ABCDEF;" align="center"| '''Product''' || small spore protein
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
+
|style="background:#ABCDEF;" align="center"|'''Function''' || spore coat assembly
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' ||  2.98 kDa, 5.27
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' ||  2.98 kDa, 5.27
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= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
 +
{{SubtiWiki regulon|[[SigK regulon]]}},
 +
{{SubtiWiki regulon|[[GerE rgulon]]}}
  
  
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===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 +
* poor [[germination]]
  
 
=== Database entries ===
 
=== Database entries ===
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=== Additional information===
 
=== Additional information===
 
  
  
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:'''
+
* '''[[SubtInteract|Interactions]]:'''
  
 
* '''Localization:'''
 
* '''Localization:'''
Line 95: Line 97:
 
=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
+
* '''Operon:''' ''sscA'' {{PubMed|21670523}}
  
* '''Sigma factor:'''  
+
* '''Sigma factor:''' [[SigK]] {{PubMed|21670523}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** expressed late during sporulation in the mother cell ([[SigK]], [[GerE]]) {{PubMed|21670523}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[GerE]]: transcription activation {{PubMed|21670523}}
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  
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=References=
 
=References=
<pubmed> 20156992 </pubmed>
+
<pubmed> 20156992 21670523 </pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 16:32, 1 July 2011

  • Description: small spore protein

Gene name sscA
Synonyms yhzE
Essential no
Product small spore protein
Function spore coat assembly
MW, pI 2.98 kDa, 5.27
Gene length, protein length 87 bp, 28 amino acids
Immediate neighbours prsA, yhaJ
Gene sequence (+200bp) Protein sequence
Genetic context
File:YhzE context.gif



Categories containing this gene/protein

toxins, antitoxins and immunity against toxins

This gene is a member of the following regulons

SigK regulon, GerE rgulon


The gene

Basic information

  • Locus tag:

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: no entry

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure:
  • KEGG entry:
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed late during sporulation in the mother cell (SigK, GerE) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Takeko Kodama, Takeshi Matsubayashi, Tadayoshi Yanagihara, Hiroyuki Komoto, Katsutoshi Ara, Katsuya Ozaki, Ritsuko Kuwana, Daisuke Imamura, Hiromu Takamatsu, Kazuhito Watabe, Junichi Sekiguchi
A novel small protein of Bacillus subtilis involved in spore germination and spore coat assembly.
Biosci Biotechnol Biochem: 2011, 75(6);1119-28
[PubMed:21670523] [WorldCat.org] [DOI] (I p)

Elizabeth M Fozo, Kira S Makarova, Svetlana A Shabalina, Natalya Yutin, Eugene V Koonin, Gisela Storz
Abundance of type I toxin-antitoxin systems in bacteria: searches for new candidates and discovery of novel families.
Nucleic Acids Res: 2010, 38(11);3743-59
[PubMed:20156992] [WorldCat.org] [DOI] (I p)