Difference between revisions of "NagR"

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m (moved YvoA to NagR: 21602348)
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|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''yvoA''
+
|''nagR''
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
+
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yvoA ''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
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= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[YvoA regulon]]}}
+
{{SubtiWiki regulon|[[NagR regulon]]}}
 
=The [[YvoA regulon]]:=
 
=The [[YvoA regulon]]:=
* ''[[nagA]]-[[nagB]]-[[yvoA]]'', ''[[nagP]]''
+
* ''[[nagA]]-[[nagB]]-[[nagR]]'', ''[[nagP]]''
  
 
=The gene=
 
=The gene=
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=== Additional information===
 
=== Additional information===
 
 
  
  
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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:''' transcription repression of ''[[nagP]]'' and of the putative ''[[nagA]]-[[nagB]]-[[yvoA]]'' operon in the absence of N-acetylglycosamine {{PubMed|20047956}}, weak repression of ''[[yflG]]'' {{PubMed|16207374}}
+
* '''Catalyzed reaction/ biological activity:''' transcription repression of ''[[nagP]]'' and of the putative ''[[nagA]]-[[nagB]]-[[nagR]]'' operon in the absence of N-acetylglycosamine {{PubMed|20047956,21602348}}, weak repression of ''[[yflG]]'' {{PubMed|16207374}}
  
 
* '''Protein family:'''
 
* '''Protein family:'''
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* '''Cofactor(s):'''
 
* '''Cofactor(s):'''
  
* '''Effectors of protein activity:''' N-acetylglucosamine-6-phosphate acts as the molecular inducer {{PubMed|20047956}}
+
* '''Effectors of protein activity:'''  
 +
** N-acetylglucosamine-6-phosphate acts as the molecular inducer {{PubMed|20047956}}
 +
** glucosamine-6-phosphate acts as the molecular inducer{{PubMed|21602348}}
  
 
* '''Interactions:'''
 
* '''Interactions:'''
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=Expression and regulation=
 
=Expression and regulation=
 
+
* '''Operon:''' ''[[nagA]]-[[nagB]]-[[nagR]]'' {{PubMed|21602348}}
* '''Operon:'''  
 
  
 
* '''[[Sigma factor]]:'''  
 
* '''[[Sigma factor]]:'''  
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** induced in the presence of N-acetylglucosamine ([[NagR]]) {{PubMed|21602348}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[NagR]]: transcription repression {{PubMed|21602348}}
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  
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=References=
 
=References=
 
+
'''Additional publications:''' {{PubMed|21602348}}
<pubmed>19342794,, 20047956 16207374</pubmed>
+
<pubmed>19342794,20047956 16207374</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 20:14, 24 May 2011

Gene name nagR
Synonyms yvoA
Essential no
Product transcriptional regulator (GntR family)
Function probably regulator of the putative nagA-nagB-yvoA operon
Metabolic function and regulation of this protein in SubtiPathways:
Sugar catabolism, Murein recycling
MW, pI 27 kDa, 6.768
Gene length, protein length 729 bp, 243 aa
Immediate neighbours nagB, yvnB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YvoA context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

utilization of specific carbon sources, transcription factors and their control

This gene is a member of the following regulons

NagR regulon

The YvoA regulon:

The gene

Basic information

  • Locus tag: BSU35030

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: transcription repression of nagP and of the putative nagA-nagB-nagR operon in the absence of N-acetylglycosamine PubMed, weak repression of yflG PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information: K(D) for N-acetylglucosamine-6-phosphate: 1 mM PubMed
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
    • N-acetylglucosamine-6-phosphate acts as the molecular inducer PubMed
    • glucosamine-6-phosphate acts as the molecular inducerPubMed
  • Interactions:
  • Localization:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • induced in the presence of N-acetylglucosamine (NagR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed