Difference between revisions of "CheW"
| Line 54: | Line 54: | ||
=== Additional information=== | === Additional information=== | ||
| − | |||
| − | |||
| − | |||
=The protein= | =The protein= | ||
| Line 116: | Line 113: | ||
** [[DegU]] (non-phosphorylated): transcription activation {{PubMed|17850253}} | ** [[DegU]] (non-phosphorylated): transcription activation {{PubMed|17850253}} | ||
| − | * '''Additional information:''' subject to Clp-dependent proteolysis upon glucose starvation [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=+17981983 PubMed] | + | * '''Additional information:''' |
| + | ** subject to Clp-dependent proteolysis upon glucose starvation [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=+17981983 PubMed] | ||
| + | ** in minimal medium, CheW is present with 2,100 +/- 430 molecules per cell {{PubMed|21515776}} | ||
=Biological materials = | =Biological materials = | ||
| Line 140: | Line 139: | ||
<pubmed> 20122866 </pubmed> | <pubmed> 20122866 </pubmed> | ||
==Original publications== | ==Original publications== | ||
| − | <pubmed>,8169224,1601874,14731274,1624415,14651647, 9657996,8157612,15175317 17850253 21098025</pubmed> | + | <pubmed>,8169224,1601874,14731274,1624415,14651647, 9657996,8157612,15175317 17850253 21098025 21515776</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 10:19, 26 April 2011
- Description: modulation of CheA activity in response to attractants, scaffold protein: facilitates coupling between CheA and receptors
| Gene name | cheW |
| Synonyms | |
| Essential | no |
| Product | CheA modulator |
| Function | control of CheA activity |
| MW, pI | 17 kDa, 4.422 |
| Gene length, protein length | 468 bp, 156 aa |
| Immediate neighbours | cheA, cheC |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
CodY regulon, SigD regulon, Spo0A regulon
The gene
Basic information
- Locus tag: BSU16440
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s): CheV (N-terminal domain)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
- cytoplasm (according to Swiss-Prot)
- predominantly present at the cell poles PubMed
Database entries
- Structure:
- UniProt: P39802
- KEGG entry: [3]
- E.C. number:
Additional information
- subject to Clp-dependent proteolysis upon glucose starvation PubMed
Expression and regulation
- Operon:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Gerald L Hazelbauer, Wing-Cheung Lai
Bacterial chemoreceptors: providing enhanced features to two-component signaling.
Curr Opin Microbiol: 2010, 13(2);124-32
[PubMed:20122866]
[WorldCat.org]
[DOI]
(I p)
Original publications
