Difference between revisions of "MetA"
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| + | = [[Categories]] containing this gene/protein = | ||
| + | {{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}}, | ||
| + | {{SubtiWiki category|[[cell envelope stress proteins (controlled by SigM, W, X, Y)]]}} | ||
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| + | = This gene is a member of the following [[regulons]] = | ||
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=The gene= | =The gene= | ||
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=The protein= | =The protein= | ||
Revision as of 20:40, 8 December 2010
- Description: homoserine O-succinyltransferase
| Gene name | metA |
| Synonyms | metB |
| Essential | no |
| Product | homoserine O-succinyltransferase |
| Function | biosynthesis of methionine |
| Metabolic function and regulation of this protein in SubtiPathways: Lys, Thr, Cys, Met & Sulfate assimilation | |
| MW, pI | 25 kDa, 6.414 |
| Gene length, protein length | 672 bp, 224 aa |
| Immediate neighbours | bsaA, ugtP |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
biosynthesis/ acquisition of amino acids, cell envelope stress proteins (controlled by SigM, W, X, Y)
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU21910
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Succinyl-CoA + L-homoserine = CoA + O-succinyl-L-homoserine (according to Swiss-Prot) O(4)-succinyl-L-homoserine + L-cysteine = L-cystathionine + succinate (according to Swiss-Prot)
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- UniProt: P54167
- KEGG entry: [3]
- E.C. number: 2.3.1.46 8 2.5.1.48]
Additional information
Expression and regulation
- Operon: metA (according to DBTBS)
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
