Difference between revisions of "YneA"
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| + | = [[Categories]] containing this gene/protein = | ||
| + | {{SubtiWiki category|[[cell division]]}} | ||
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| + | = This gene is a member of the following [[regulons]] = | ||
| + | {{SubtiWiki regulon|[[LexA regulon]]}} | ||
=The gene= | =The gene= | ||
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=The protein= | =The protein= | ||
Revision as of 20:03, 8 December 2010
- Description: inhibits cell division during SOS response
| Gene name | yneA |
| Synonyms | |
| Essential | no |
| Product | cell division control protein |
| Function | inhibits cell division during SOS response |
| MW, pI | 11 kDa, 4.613 |
| Gene length, protein length | 315 bp, 105 aa |
| Immediate neighbours | lexA, yneB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU17860
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: yneA family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- LysM peptidoglycan binding domain PubMed
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: secreted to the medium (signal peptide) PubMed
Database entries
- Structure:
- UniProt: Q45056
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
- YneA is rapidly degraded by extracellular proteases PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Allison H Mo, William F Burkholder
YneA, an SOS-induced inhibitor of cell division in Bacillus subtilis, is regulated posttranslationally and requires the transmembrane region for activity.
J Bacteriol: 2010, 192(12);3159-73
[PubMed:20400548]
[WorldCat.org]
[DOI]
(I p)
Nora Au, Elke Kuester-Schoeck, Veena Mandava, Laura E Bothwell, Susan P Canny, Karen Chachu, Sierra A Colavito, Shakierah N Fuller, Eli S Groban, Laura A Hensley, Theresa C O'Brien, Amish Shah, Jessica T Tierney, Louise L Tomm, Thomas M O'Gara, Alexi I Goranov, Alan D Grossman, Charles M Lovett
Genetic composition of the Bacillus subtilis SOS system.
J Bacteriol: 2005, 187(22);7655-66
[PubMed:16267290]
[WorldCat.org]
[DOI]
(P p)
Yoshikazu Kawai, Shigeki Moriya, Naotake Ogasawara
Identification of a protein, YneA, responsible for cell division suppression during the SOS response in Bacillus subtilis.
Mol Microbiol: 2003, 47(4);1113-22
[PubMed:12581363]
[WorldCat.org]
[DOI]
(P p)
