RsgI

• Description: regulator of SigI activity
  
  

Gene name	rsgI
Synonyms	ykrI
Essential	no
Product	anti-sigma factor
Function	control of SigI activity
Metabolic function and regulation of this protein in SubtiPathways: Stress
MW, pI	43 kDa, 4.517
Gene length, protein length	1143 bp, 381 aa
Immediate neighbours	sigI, sspD
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU13460

Phenotypes of a mutant

suppresses the growth defect of a mbl mutation PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

sigma factors and their control, heat shock proteins, membrane proteins

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: anti-sigma factor for SigI PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: RsgI-SigI PubMed

• Localization: membrane PubMed

Database entries

• Structure:

• UniProt: O31655

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: sigI-rsgI PubMed

• Sigma factor: SigI PubMed

• Regulation: induced by heat PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Kathrin Schirner, Jeff Errington
The cell wall regulator {sigma}I specifically suppresses the lethal phenotype of mbl mutants in Bacillus subtilis.
J Bacteriol: 2009, 191(5);1404-13
[PubMed:19114499] [WorldCat.org] [DOI] (I p)

Kei Asai, Takafumi Ootsuji, Kazue Obata, Takashi Matsumoto, Yasutaro Fujita, Yoshito Sadaie
Regulatory role of RsgI in sigI expression in Bacillus subtilis.
Microbiology (Reading): 2007, 153(Pt 1);92-101
[PubMed:17185538] [WorldCat.org] [DOI] (P p)