ResB

• Description: part of haem translocase, required for cytochrome c synthesis
  
  

Gene name	resB
Synonyms	ypxB
Essential	yes PubMed
Product	part of the ResB-ResC haem translocase
Function	cytochrome c biogenesis
MW, pI	61 kDa, 9.474
Gene length, protein length	1626 bp, 542 aa
Immediate neighbours	resC, resA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU23140

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

respiration, essential genes, membrane proteins

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: haem-binding protein, translocation of haem from the cytoplasmic to the extracytoplasmic site of the membrane PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: ResB-ResC PubMed

• Localization: cell membrane ResB-ResC PubMed

Database entries

• Structure:

• UniProt: P35161

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: resA-resB-resC-resD-resE PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • expressed under anaerobic conditions (ResD) PubMed
  • expressed under conditions of phosphate limitation (PhoP) PubMed
  • repressed by glucose (CcpA) PubMed

• Regulatory mechanism:
  • ResD: transcription activation PubMed
  • PhoP: transcription activation PubMed
  • CcpA: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: