Difference between revisions of "BioW"

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(Expression and regulation)
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= Categories containing this gene/protein =
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{{SubtiWiki category|[[biosynthesis of cofactors]]}}
 
=The protein=
 
=The protein=
  

Revision as of 15:26, 30 November 2010

  • Description: 6-carboxyhexanoate-CoA ligase

Gene name bioW
Synonyms
Essential no
Product 6-carboxyhexanoate-CoA ligase)
Function biosynthesis of biotin
MW, pI 29 kDa, 5.548
Gene length, protein length 777 bp, 259 aa
Immediate neighbours bioA, ytaP
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
BioW context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU30240

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

Categories containing this gene/protein

biosynthesis of cofactors

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + 6-carboxyhexanoate + CoA = AMP + diphosphate + 6-carboxyhexanoyl-CoA (according to Swiss-Prot)
  • Protein family: bioW family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • repressed in the presence of biotin (BirA) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References