Difference between revisions of "Phosphorelay"
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* 4.2.4. [[Germination]] | * 4.2.4. [[Germination]] | ||
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| − | + | * [[two-component systems]] | |
| + | * [[response regulator aspartate phosphatases]] | ||
| + | * [[phosphoproteins]] | ||
| + | * [[protein kinases and phosphatases]] | ||
|}} | |}} | ||
| + | |||
| + | __TOC__ | ||
| + | <br><br><br> | ||
| + | The phosphorelay is a complex variation of a [[two-component systems|two-component regulatory system]]. It includes phosphotransferases that transfer the phosphoryl group from the sensor kinases to the ultimate target. The sporulation initiation phosphorelay is the paradigm of this class of signal transduction systems. | ||
| + | |||
| + | ==The kinases== | ||
| + | * [[KinA]] (controlled by [[Sda]], [[KipI]], and [[KipA]]) | ||
| + | * [[KinB]] (controlled by [[Sda]], [[KbaA]], and [[KapB]]) | ||
| + | * [[KinC]] | ||
| + | * [[KinD]] | ||
| + | * [[KinE]] | ||
| + | |||
| + | ==The phosphotransferases== | ||
| + | * [[Spo0F]] | ||
| + | * [[Spo0B]] | ||
| + | |||
| + | ==The ultimate target== | ||
| + | * [[Spo0A]] | ||
| + | |||
| + | ==Phosphatases controlling the phosphorelay (and peptides that modulate their activity)== | ||
| + | * [[Spo0E]]: dephosphorylation of [[Spo0A]] | ||
| + | * [[YisI]]: dephosphorylation of [[Spo0A]] | ||
| + | * [[YnzD]]: dephosphorylation of [[Spo0A]] | ||
| + | * [[RapA]], [[PhrA]]: dephosphorylation of [[Spo0F]] | ||
| + | * [[RapB]]: dephosphorylation of [[Spo0F]] | ||
| + | * [[RapE]], [[PhrE]]: dephosphorylation of [[Spo0F]] | ||
| + | * [[RapH]]: dephosphorylation of [[Spo0F]] | ||
| + | |||
| + | ==A mathematical model== | ||
| + | <pubmed> 20238180 </pubmed> | ||
| + | ==Reviews== | ||
| + | <pubmed>8730857 11587783 9778730 1664534 12406209 11489844 10745001 8432743 19995980 19943903 20133180 20154131 </pubmed> | ||
Revision as of 12:43, 12 November 2010
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Contents
The phosphorelay is a complex variation of a two-component regulatory system. It includes phosphotransferases that transfer the phosphoryl group from the sensor kinases to the ultimate target. The sporulation initiation phosphorelay is the paradigm of this class of signal transduction systems.
The kinases
The phosphotransferases
The ultimate target
Phosphatases controlling the phosphorelay (and peptides that modulate their activity)
- Spo0E: dephosphorylation of Spo0A
- YisI: dephosphorylation of Spo0A
- YnzD: dephosphorylation of Spo0A
- RapA, PhrA: dephosphorylation of Spo0F
- RapB: dephosphorylation of Spo0F
- RapE, PhrE: dephosphorylation of Spo0F
- RapH: dephosphorylation of Spo0F
A mathematical model
Sara Jabbari, John T Heap, John R King
Mathematical modelling of the sporulation-initiation network in Bacillus subtilis revealing the dual role of the putative quorum-sensing signal molecule PhrA.
Bull Math Biol: 2011, 73(1);181-211
[PubMed:20238180]
[WorldCat.org]
[DOI]
(I p)
Reviews
