Difference between revisions of "FeuA"
(→Labs working on this gene/protein) |
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* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
− | * '''Interactions:''' | + | * '''Interactions:''' |
+ | ** [[YusV]]-([[FeuB]]-[[FeuC]])-[[FeuA]] {{PubMed|10092453}} | ||
− | * '''Localization:''' | + | * '''Localization:''' |
+ | ** associated to the membrane (via [[FeuB]]-[[FeuC]]) {{PubMed|10092453,18763711}} | ||
+ | ** extracellular (signal peptide) [http://www.ncbi.nlm.nih.gov/pubmed/18957862 PubMed] | ||
=== Database entries === | === Database entries === |
Revision as of 19:31, 4 November 2010
- Description: ABC transporter for the siderophores Fe-enterobactin and Fe-bacillibactin (binding protein), with YusV as ATPase
Gene name | feuA |
Synonyms | |
Essential | no |
Product | ABC transporter for the siderophores Fe-enterobactin and Fe-bacillibactin (binding protein) |
Function | iron acquisition |
Metabolic function and regulation of this protein in SubtiPathways: Stress | |
MW, pI | 34 kDa, 8.018 |
Gene length, protein length | 951 bp, 317 aa |
Immediate neighbours | feuB, btr |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU01630
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/biological activity:
Substrate binding protein for the triscatecholate siderophores ferri-bacillibactin and ferri-enterobactin and part of the FeuA-FeuB-FeuC-YusV ATP-binding cassette-type transporter. Furthermore ferric complexes of L-norepinephrine are bound by this protein.
- Protein family: Fe/B12 periplasmic-binding domain (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
Two independent non-symmetric globular domains, connected by a long alpha-helix (residues 143-164 of the mature protein).
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- UniProt: P40409
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References