Difference between revisions of "CwlP"
| Line 1: | Line 1: | ||
| − | * '''Description:''' | + | * '''Description:''' cell wall hydrolase of the SP-beta prophage region, <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Gene name''' | |style="background:#ABCDEF;" align="center"|'''Gene name''' | ||
| − | |'' | + | |''cwlP'' |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' '' | + | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yomI '' |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || cell wall hydrolase |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || cell wall turnover | |style="background:#ABCDEF;" align="center"|'''Function''' || cell wall turnover | ||
| Line 54: | Line 54: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' hydrolyzes the peptidoglycan and cell wall of ''B. subtilis'' {{PubMed|20980266}} |
* '''Protein family:''' FPP/GGPP synthetase family (according to Swiss-Prot) | * '''Protein family:''' FPP/GGPP synthetase family (according to Swiss-Prot) | ||
| Line 64: | Line 64: | ||
* '''Kinetic information:''' | * '''Kinetic information:''' | ||
| − | * '''Domains:''' | + | * '''Domains:''' contains soluble lytic transglycosylase (SLT) and peptidase M23 domains {{PubMed|20980266}} |
* '''Modification:''' | * '''Modification:''' | ||
| Line 119: | Line 119: | ||
=References= | =References= | ||
| − | + | <pubmed> 20980266 </pubmed> | |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:03, 29 October 2010
- Description: cell wall hydrolase of the SP-beta prophage region,
| Gene name | cwlP |
| Synonyms | yomI |
| Essential | no |
| Product | cell wall hydrolase |
| Function | cell wall turnover |
| MW, pI | 252 kDa, 8.268 |
| Gene length, protein length | 6855 bp, 2285 aa |
| Immediate neighbours | yomJ, yomH |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU21350
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: hydrolyzes the peptidoglycan and cell wall of B. subtilis PubMed
- Protein family: FPP/GGPP synthetase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains: contains soluble lytic transglycosylase (SLT) and peptidase M23 domains PubMed
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: O31976
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
I Putu Sudiarta, Tatsuya Fukushima, Junichi Sekiguchi
Bacillus subtilis CwlP of the SP-{beta} prophage has two novel peptidoglycan hydrolase domains, muramidase and cross-linkage digesting DD-endopeptidase.
J Biol Chem: 2010, 285(53);41232-43
[PubMed:20980266]
[WorldCat.org]
[DOI]
(I p)
