Difference between revisions of "RtpA"

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(References)
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:''' [[MtrB|TRAP]]-[[RtpA]] {{PubMed|11557884}}
+
* '''Interactions:''' [[MtrB|TRAP]]-[[RtpA]] {{PubMed|11557884}}, forms trimers and dodecamers (tetramer of trimers) {{PubMed|20713740}}, only the trimeric form interacts with [[MtrB|TRAP]] {{PubMed|20713740}}
  
 
* '''Localization:''' cytoplasm (according to Swiss-Prot)
 
* '''Localization:''' cytoplasm (according to Swiss-Prot)
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<pubmed>16285852, 19258532,</pubmed>
 
<pubmed>16285852, 19258532,</pubmed>
 
==Original Publications==
 
==Original Publications==
<pubmed>15213402,16306262,15099736,15743934,11786553,11566976,15023340,18178730,12386162,11557884,10706627,18334255,12855807, </pubmed>
+
<pubmed>15213402,16306262,15099736,15743934,11786553,11566976,15023340,18178730,12386162,11557884,10706627,18334255,12855807, 20713740 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 08:20, 18 August 2010

  • Description: anti-TRAP

Gene name rtpA
Synonyms yczA
Essential no
Product anti-TRAP
Function regulation of tryptophan biosynthesis
Metabolic function and regulation of this protein in SubtiPathways:
Phe, Tyr, Trp
MW, pI 5 kDa, 4.862
Gene length, protein length 159 bp, 53 aa
Immediate neighbours ycbJ, ycbK
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YczA context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU02530

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Ana Gutiérrez-Preciado, Tina M Henkin, Frank J Grundy, Charles Yanofsky, Enrique Merino
Biochemical features and functional implications of the RNA-based T-box regulatory mechanism.
Microbiol Mol Biol Rev: 2009, 73(1);36-61
[PubMed:19258532] [WorldCat.org] [DOI] (I p)

Paul Gollnick, Paul Babitzke, Alfred Antson, Charles Yanofsky
Complexity in regulation of tryptophan biosynthesis in Bacillus subtilis.
Annu Rev Genet: 2005, 39;47-68
[PubMed:16285852] [WorldCat.org] [DOI] (P p)

Original Publications