Difference between revisions of "IolT"

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(Expression and regulation)
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|style="background:#ABCDEF;" align="center"| '''Product''' || major transporter for inositol  
 
|style="background:#ABCDEF;" align="center"| '''Product''' || major transporter for inositol  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || inositol uptake
+
|style="background:#ABCDEF;" align="center"|'''Function''' || myo-inositol uptake
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 51 kDa, 9.569   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 51 kDa, 9.569   
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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:'''  
+
* '''Catalyzed reaction/ biological activity:''' transport of myo-inositol {{PubMed|20530884}}
  
 
* '''Protein family:''' View classification (according to Swiss-Prot)
 
* '''Protein family:''' View classification (according to Swiss-Prot)
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=References=
 
=References=
  
<pubmed>11807058,,11807058, </pubmed>
+
<pubmed>11807058, 20530884 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 10:40, 10 June 2010

  • Description: major transporter for inositol

Gene name iolT
Synonyms ydjK
Essential no
Product major transporter for inositol
Function myo-inositol uptake
MW, pI 51 kDa, 9.569
Gene length, protein length 1419 bp, 473 aa
Immediate neighbours ydjJ, bdhA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YdjK context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU06230

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: transport of myo-inositol PubMed
  • Protein family: View classification (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
    • induced in the presence of inositol (IolR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Tetsuro Morinaga, Takatsugu Matsuse, Hitoshi Ashida, Ken-ichi Yoshida
Differential substrate specificity of two inositol transporters of Bacillus subtilis.
Biosci Biotechnol Biochem: 2010, 74(6);1312-4
[PubMed:20530884] [WorldCat.org] [DOI] (I p)

Ken-Ichi Yoshida, Yoshiyuki Yamamoto, Kaoru Omae, Mami Yamamoto, Yasutaro Fujita
Identification of two myo-inositol transporter genes of Bacillus subtilis.
J Bacteriol: 2002, 184(4);983-91
[PubMed:11807058] [WorldCat.org] [DOI] (P p)