Difference between revisions of "YneA"

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* '''Domains:'''  
 
* '''Domains:'''  
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** LysM peptidoglycan binding domain {{PubMed|20400548}}
  
 
* '''Modification:'''
 
* '''Modification:'''
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* '''Interactions:'''
 
* '''Interactions:'''
  
* '''Localization:''' cytoplasm (according to Swiss-Prot)
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* '''Localization:''' secreted to the medium (signal peptide) {{PubMed|20400548}}
  
 
=== Database entries ===
 
=== Database entries ===
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* '''Additional information:'''  
 
* '''Additional information:'''  
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** YneA is rapidly degraded by extracellular proteases {{PubMed|20400548}}
  
 
=Biological materials =
 
=Biological materials =
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=References=
 
=References=
<pubmed>12581363, </pubmed>
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<pubmed>12581363, 20400548 </pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 11:49, 20 April 2010

  • Description: inhibits cell division during SOS response

Gene name yneA
Synonyms
Essential no
Product cell division control protein
Function inhibits cell division during SOS response
MW, pI 11 kDa, 4.613
Gene length, protein length 315 bp, 105 aa
Immediate neighbours lexA, yneB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YneA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU17860

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: yneA family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
    • LysM peptidoglycan binding domain PubMed
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: secreted to the medium (signal peptide) PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:
    • YneA is rapidly degraded by extracellular proteases PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Allison H Mo, William F Burkholder
YneA, an SOS-induced inhibitor of cell division in Bacillus subtilis, is regulated posttranslationally and requires the transmembrane region for activity.
J Bacteriol: 2010, 192(12);3159-73
[PubMed:20400548] [WorldCat.org] [DOI] (I p)

Yoshikazu Kawai, Shigeki Moriya, Naotake Ogasawara
Identification of a protein, YneA, responsible for cell division suppression during the SOS response in Bacillus subtilis.
Mol Microbiol: 2003, 47(4);1113-22
[PubMed:12581363] [WorldCat.org] [DOI] (P p)