PgcM

• Description: beta-phosphoglucomutase
  
  

Gene name	pgcM
Synonyms	yvdM
Essential	no
Product	beta-phosphoglucomutase (EC 5.4.2.6 and EC 2.7.1.41)
Function	starch and maltodextrin utilization
Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism
MW, pI	24 kDa, 4.76
Gene length, protein length	678 bp, 226 aa
Immediate neighbours	clpP, malL
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU34550

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate (according to Swiss-Prot)

• Protein family: CbbY/cbbZ/gph/yieH family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 1ZOL (from Lactococcus lactis, 48% identity, 66% similarity) PubMed

• UniProt: O06995

• KEGG entry: [2]

• E.C. number: 5.4.2.6

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Stefan Schönert, Sabine Seitz, Holger Krafft, Eva-Anne Feuerbaum, Iris Andernach, Gabriele Witz, Michael K Dahl
Maltose and maltodextrin utilization by Bacillus subtilis.
J Bacteriol: 2006, 188(11);3911-22
[PubMed:16707683] [WorldCat.org] [DOI] (P p)

L R Mesak, M K Dahl
Purification and enzymatic characterization of PgcM: a beta-phosphoglucomutase and glucose-1-phosphate phosphodismutase of Bacillus subtilis.
Arch Microbiol: 2000, 174(4);256-64
[PubMed:11081794] [WorldCat.org] [DOI] (P p)