Difference between revisions of "ScoA"

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=Expression and regulation=
 
=Expression and regulation=
 +
* '''Operon:''' ''[[yxjC]]-[[scoA]]-[[scoB]]-[[yxjF]]'' {{PubMed|10746760}}
  
* '''Operon:''' ''[[yxjC]]-[[scoA]]-[[scoB]]-[[yxjF]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/10746760 PubMed]
+
* '''[[Sigma factor]]:''' [[SigE]] {{PubMed|12662922}}
 
 
* '''[[Sigma factor]]:''' [[SigE]] {{PubMed|15699190}}
 
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** repressed by glucose ([[CcpA]]) {{PubMed|12850135,10666464}} 
 +
** expressed early during sporulation in the mother cell ([[SigE]]) {{PubMed|12662922}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[CcpA]]: transcription repression {{PubMed|12850135,10666464}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''
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=References=
 
=References=
  
<pubmed>17363272,,16672620,, </pubmed>
+
<pubmed>17363272,10746760,16672620,12662922,12850135,10666464 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 10:34, 7 February 2010

  • Description: probable succinyl CoA:3-oxoacid CoA-transferase (subunit A)

Gene name scoA
Synonyms yxjD
Essential no
Product probable succinyl CoA:3-oxoacid CoA-transferase (subunit A)
Function lipid metabolism
MW, pI 25 kDa, 6.613
Gene length, protein length 714 bp, 238 aa
Immediate neighbours scoB, yxjC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
ScoA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU38990

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Succinyl-CoA + a 3-oxo acid = succinate + a 3-oxoacyl-CoA (according to Swiss-Prot)
  • Protein family: 3-oxoacid CoA-transferase subunit A family (according to Swiss-Prot)
  • Paralogous protein(s): YodS

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • repressed by glucose (CcpA) PubMed
    • expressed early during sporulation in the mother cell (SigE) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References