Difference between revisions of "GalE"
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=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''galE'' {{PubMed|10746760}} |
| − | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|9555917}} |
* '''Regulation:''' | * '''Regulation:''' | ||
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* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 10:18, 7 February 2010
- Description: UDP glucose 4-epimerase
| Gene name | galE |
| Synonyms | |
| Essential | no |
| Product | UDP glucose 4-epimerase |
| Function | galactose utilization |
| Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism | |
| MW, pI | 36 kDa, 4.776 |
| Gene length, protein length | 1017 bp, 339 aa |
| Immediate neighbours | yxkC, yxkA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU38860
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: UDP-glucose = UDP-galactose (according to Swiss-Prot)
- Protein family: sugar epimerase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P55180
- KEGG entry: [3]
- E.C. number: 5.1.3.2
Additional information
Expression and regulation
- Operon: galE PubMed
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Blazenka Soldo, Claudio Scotti, Dimitri Karamata, Vladimir Lazarevic
The Bacillus subtilis Gne (GneA, GalE) protein can catalyse UDP-glucose as well as UDP-N-acetylglucosamine 4-epimerisation.
Gene: 2003, 319;65-9
[PubMed:14597172]
[WorldCat.org]
[DOI]
(P p)
O Krispin, R Allmansberger
The Bacillus subtilis galE gene is essential in the presence of glucose and galactose.
J Bacteriol: 1998, 180(8);2265-70
[PubMed:9555917]
[WorldCat.org]
[DOI]
(P p)
