Difference between revisions of "DltD"
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=Expression and regulation= | =Expression and regulation= | ||
| + | * '''Operon:''' ''[[dltA]]-[[dltB]]-[[dltC]]-[[dltD]]-[[dltE]]'' {{PubMed|7797557}} | ||
| − | + | * '''[[Sigma factor]]:''' [[SigD]] {{PubMed|7797557}}, [[SigX]] {{PubMed|14762009}} | |
| − | |||
| − | * '''[[Sigma factor]]:''' [[SigD]], [[SigX]] | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| − | + | ** [[RelA]] dependent downregulation (Class I) during stringent response {{PubMed|11948165}} | |
| − | ** [[RelA]] dependent downregulation (Class I) during stringent response {{PubMed|11948165}} | + | ** repressed under conditions that trigger sporulation ([[Spo0A]]) {{PubMed|7797557}} |
| − | ** repressed under conditions that trigger sporulation ([[Spo0A]]) | ||
| − | * '''Regulatory mechanism:''' activated by [[YvrHb]] [http://www.ncbi.nlm.nih.gov/sites/entrez/16306698 PubMed] | + | * '''Regulatory mechanism:''' |
| − | ** [[Spo0A]]: transcription repression | + | ** activated by [[YvrHb]] [http://www.ncbi.nlm.nih.gov/sites/entrez/16306698 PubMed] |
| + | ** [[Spo0A]]: transcription repression {{PubMed|7797557}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
Revision as of 10:18, 6 February 2010
- Description: D-alanine transfer from undecaprenol-phosphate to the poly(glycerophosphate) chain
| Gene name | dltD |
| Synonyms | ipa-2r |
| Essential | no |
| Product | D-alanine transfer from undecaprenol-phosphate to the poly(glycerophosphate) chain |
| Function | biosynthesis of teichoic acid |
| MW, pI | 44 kDa, 9.858 |
| Gene length, protein length | 1176 bp, 392 aa |
| Immediate neighbours | dltC, dltE |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU38530
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P39578
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Hanne-Leena Hyyryläinen, Milla Pietiäinen, Tuula Lundén, Anna Ekman, Marika Gardemeister, Sanna Murtomäki-Repo, Haike Antelmann, Michael Hecker, Leena Valmu, Matti Sarvas, Vesa P Kontinen
The density of negative charge in the cell wall influences two-component signal transduction in Bacillus subtilis.
Microbiology (Reading): 2007, 153(Pt 7);2126-2136
[PubMed:17600057]
[WorldCat.org]
[DOI]
(P p)
Min Cao, John D Helmann
The Bacillus subtilis extracytoplasmic-function sigmaX factor regulates modification of the cell envelope and resistance to cationic antimicrobial peptides.
J Bacteriol: 2004, 186(4);1136-46
[PubMed:14762009]
[WorldCat.org]
[DOI]
(P p)
Hans-Matti Blencke, Georg Homuth, Holger Ludwig, Ulrike Mäder, Michael Hecker, Jörg Stülke
Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways.
Metab Eng: 2003, 5(2);133-49
[PubMed:12850135]
[WorldCat.org]
[DOI]
(P p)
H L Hyyrylainen, M Vitikainen, J Thwaite, H Wu, M Sarvas, C R Harwood, V P Kontinen, K Stephenson
D-Alanine substitution of teichoic acids as a modulator of protein folding and stability at the cytoplasmic membrane/cell wall interface of Bacillus subtilis.
J Biol Chem: 2000, 275(35);26696-703
[PubMed:10871614]
[WorldCat.org]
[DOI]
(P p)
M Perego, P Glaser, A Minutello, M A Strauch, K Leopold, W Fischer
Incorporation of D-alanine into lipoteichoic acid and wall teichoic acid in Bacillus subtilis. Identification of genes and regulation.
J Biol Chem: 1995, 270(26);15598-606
[PubMed:7797557]
[WorldCat.org]
[DOI]
(P p)
