Difference between revisions of "GalK"
| Line 89: | Line 89: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | + | * '''Operon:''' ''[[galK]]-[[galT]]'' {{PubMed|9353933}} | |
| − | * '''Operon:''' [[galK]]-[[galT]] | ||
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
| − | * '''Regulation:''' repressed by glucose ([[CcpA]]) | + | * '''Regulation:''' |
| + | ** repressed by glucose ([[CcpA]]) {{PubMed|10666464}} | ||
| − | * '''Regulatory mechanism:''' [[CcpA]]: transcription repression | + | * '''Regulatory mechanism:''' |
| + | ** [[CcpA]]: transcription repression {{PubMed|10666464}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 119: | Line 120: | ||
=References= | =References= | ||
| − | + | <pubmed>9353933 10666464</pubmed> | |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 20:29, 4 February 2010
- Description: galactokinase
| Gene name | galK |
| Synonyms | ipa-35d |
| Essential | no |
| Product | galactokinase |
| Function | galactose utilization |
| Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism | |
| MW, pI | 43 kDa, 5.148 |
| Gene length, protein length | 1170 bp, 390 aa |
| Immediate neighbours | galT, gtaC |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU38200
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + D-galactose = ADP + alpha-D-galactose 1-phosphate (according to Swiss-Prot)
- Protein family: GalK subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P39574
- KEGG entry: [3]
- E.C. number: 2.7.1.6
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
