Difference between revisions of "Mbl"

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(References)
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=Expression and regulation=
 
=Expression and regulation=
 +
* '''Operon:''' ''[[usd]]-[[spoIIID]]-[[mbl]]-[[flhO]]-[[fhlP]]'' {{PubMed|9023218,7836311}}
  
* '''Operon:'''
+
* '''[[Sigma factor]]:''' [[SigE]] {{PubMed|9023218}}  
 
 
* '''[[Sigma factor]]:''' [[SigE]] {{PubMed|15699190}}
 
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** expressed early during sporulation in the mother cell ([[SigE]]) {{PubMed|9023218}}
 
** [[RelA]] dependent downregulation (Class I) during stringent response {{PubMed|11948165}}
 
** [[RelA]] dependent downregulation (Class I) during stringent response {{PubMed|11948165}}
  
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=References=
 
=References=
  
<pubmed>19643765 19114499,16832063,11290328,12809607,16101995,12530960,7836311,,16950129 17064365 19659933 19114499, </pubmed>
+
<pubmed>19643765,16832063,11290328,12809607,16101995,12530960,7836311,,16950129 17064365 9023218, 19659933 19114499, </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 22:37, 29 January 2010

  • Description: cell-shape determining protein

Gene name mbl
Synonyms
Essential no
Product MreB-like protein
Function cell-shape determination
MW, pI 35 kDa, 5.669
Gene length, protein length 999 bp, 333 aa
Immediate neighbours flhO, spoIIID
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
Mbl context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU36410

Phenotypes of a mutant

non-viable in the presence of low Mg(2+), readily accumulate rsgI suppressor mutants PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: ftsA/mreB family (according to Swiss-Prot)

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: forms helical structures close to the inner surface of the cytoplasmic membrane PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed early during sporulation in the mother cell (SigE) PubMed
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:

Labs working on this gene/protein

Peter Graumann, Freiburg University, Germany homepage

Your additional remarks

References