Difference between revisions of "Pdp"
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* '''Operon:''' | * '''Operon:''' | ||
| − | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' |
* '''Regulation:''' repressed by glucose ([[CcpA]]) | * '''Regulation:''' repressed by glucose ([[CcpA]]) | ||
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* '''Regulatory mechanism:''' [[CcpA]]: transcription repression | * '''Regulatory mechanism:''' [[CcpA]]: transcription repression | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 19:56, 28 January 2010
- Description: pyrimidine nucleoside phosphorylase
| Gene name | pdp |
| Synonyms | |
| Essential | no |
| Product | pyrimidine nucleoside phosphorylase |
| Function | pyrimidine interconversion |
| Metabolic function and regulation of this protein in SubtiPathways: Nucleoside catabolism, Nucleotides (regulation) | |
| MW, pI | 46 kDa, 4.765 |
| Gene length, protein length | 1299 bp, 433 aa |
| Immediate neighbours | hutM, nupC |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU39400
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: A pyrimidine nucleoside + phosphate = a pyrimidine base + alpha-D-ribose 1-phosphate (according to Swiss-Prot)
- Protein family: thymidine/pyrimidine-nucleoside phosphorylase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure: 1BRW (Geobacillus stearothermophilus)
- UniProt: P39142
- KEGG entry: [3]
- E.C. number: 2.4.2.2
Additional information
Expression and regulation
- Operon:
- Regulation: repressed by glucose (CcpA)
- Regulatory mechanism: CcpA: transcription repression
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
