Difference between revisions of "DegS"
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=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon: | + | * '''Operon:''' ''[[degS]]-[[degU]]'' {{PubMed|1688843}} |
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|1688843}} | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|1688843}} | ||
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=References= | =References= | ||
| − | <pubmed>17850253,12471443,14563871,1459944,1901568,10094672,,16479537, 17218307 </pubmed> | + | <pubmed>17850253,12471443,14563871,1459944,1901568,10094672,1688843 ,16479537, 17218307 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 20:47, 4 January 2010
- Description: two-component sensor kinase for exoenzyme and competence regulation
| Gene name | degS |
| Synonyms | sacU |
| Essential | no |
| Product | two-component sensor kinase |
| Function | regulation of degradative enzyme and genetic competence |
| MW, pI | 44 kDa, 5.988 |
| Gene length, protein length | 1155 bp, 385 aa |
| Immediate neighbours | degU, yvyE |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU35500
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: autophosphorylation, autodephosphorylation, phosphorylation of DegU on Asp-56 PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- aa 12 ... 170: unknown DegS domain
- aa 180 ... 248: HisKA_3 domain (autophosphorylation)
- aa 289 ... 384: HATPase_c
- Modification: phosphorylation on Ser-76 PubMed, autophosphorylation on His-189
- Cofactor(s):
- Effectors of protein activity: DegQ
- Localization: Cytoplasm (Homogeneous) PubMed
Database entries
- Structure:
- UniProt: P13799
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Tarek Msadek, Institut Pasteur, Paris, France
Your additional remarks
References
