Difference between revisions of "SlrR"
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| − | * '''Description:''' transcriptional activator of competence development and sporulation genes, represses [[SigD]]-dependent flagellar genes | + | * '''Description:''' transcriptional activator of competence development and sporulation genes, represses [[SigD]]-dependent flagellar genes, antagonist of [[SlrA]] <br/><br/> |
| − | + | [[Link title]] | |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || transcription regulator | + | |style="background:#ABCDEF;" align="center"| '''Product''' || transcription regulator, [[SrlA]] antagonist |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of initiation of biofilm formation | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of initiation of biofilm formation | ||
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=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' binding and concomintant inactivation of [[SlrA]] results in release of [[SinR]] from the [[SinR]]-[[SrlA]] complex and subsequent induction of [[SinR]]-controlled genes and operons for biofilm formation {{PubMed|19788541}} |
* '''Protein family:''' | * '''Protein family:''' | ||
| Line 95: | Line 95: | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | ** | + | ** [[Abh]]: transcription activation {{PubMed|19767430}} |
| + | ** [[SinR]]: transcription repression {{PubMed|19788541}} | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
| + | ** induction by sequestration of [[SinR]] by [[SinI]] or [[SrlA]] {{PubMed|15661000,19788541}} | ||
=Biological materials = | =Biological materials = | ||
Revision as of 09:55, 30 December 2009
- Description: transcriptional activator of competence development and sporulation genes, represses SigD-dependent flagellar genes, antagonist of SlrA
| Gene name | slrR |
| Synonyms | yveJ, slr |
| Essential | no |
| Product | transcription regulator, SrlA antagonist |
| Function | regulation of initiation of biofilm formation |
| MW, pI | 17 kDa, 9.63 |
| Gene length, protein length | 456 bp, 152 aa |
| Immediate neighbours | epsA, pnbA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU34380
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: binding and concomintant inactivation of SlrA results in release of SinR from the SinR-SrlA complex and subsequent induction of SinR-controlled genes and operons for biofilm formation PubMed
- Protein family:
- Paralogous protein(s): SinR
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure:
- UniProt: P71049
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
