Difference between revisions of "AzoR2"
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=Expression and regulation= | =Expression and regulation= | ||
| + | * '''Operon:''' ''azoR2'' {{PubMed|17725564}} | ||
| − | * ''' | + | * '''Sigma factor:''' [[SigA]] {{PubMed|17725564}}, SigG {{PubMed|16497325}} |
| − | * ''' | + | * '''Regulation:''' |
| − | + | ** induced by catechol and 2-methylhydroquinone (2-MHQ) ([[MhqR]]) {{PubMed|17725564}} | |
| − | * | + | ** repressed by casamino acids [http://www.ncbi.nlm.nih.gov/pubmed/12107147 PubMed] |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[MhqR]]: transcription repression {{PubMed|17725564}} | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 10:10, 29 December 2009
- Description: similar to NAD(P)H dehydrogenase (quinone)
| Gene name | azoR2 |
| Synonyms | yvaB |
| Essential | no |
| Product | azoreductase |
| Function | resistance to 2-methylhydroquinone |
| MW, pI | 23 kDa, 5.114 |
| Gene length, protein length | 633 bp, 211 aa |
| Immediate neighbours | yvaA, yvaC |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU33540
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: azoreductase type 1 family (according to Swiss-Prot)
- Paralogous protein(s): AzoR1
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: O32224
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: azoR2 PubMed
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Montira Leelakriangsak, Nguyen Thi Thu Huyen, Stefanie Töwe, Nguyen van Duy, Dörte Becher, Michael Hecker, Haike Antelmann, Peter Zuber
Regulation of quinone detoxification by the thiol stress sensing DUF24/MarR-like repressor, YodB in Bacillus subtilis.
Mol Microbiol: 2008, 67(5);1108-24
[PubMed:18208493]
[WorldCat.org]
[DOI]
(I p)
Stefanie Töwe, Montira Leelakriangsak, Kazuo Kobayashi, Nguyen Van Duy, Michael Hecker, Peter Zuber, Haike Antelmann
The MarR-type repressor MhqR (YkvE) regulates multiple dioxygenases/glyoxalases and an azoreductase which confer resistance to 2-methylhydroquinone and catechol in Bacillus subtilis.
Mol Microbiol: 2007, 66(1);40-54
[PubMed:17725564]
[WorldCat.org]
[DOI]
(P p)
Ulrike Mäder, Georg Homuth, Christian Scharf, Knut Büttner, Rüdiger Bode, Michael Hecker
Transcriptome and proteome analysis of Bacillus subtilis gene expression modulated by amino acid availability.
J Bacteriol: 2002, 184(15);4288-95
[PubMed:12107147]
[WorldCat.org]
[DOI]
(P p)
