Difference between revisions of "ResE"

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(The protein)
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* '''Regulation:'''  
 
* '''Regulation:'''  
 
** expressed under anaerobic conditions ([[ResD]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/8631715,11222591 PubMed]
 
** expressed under anaerobic conditions ([[ResD]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/8631715,11222591 PubMed]
** repressed when phosphate is available ([[PhoP]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/9988472 PubMed]
+
** expressed under conditions of phosphate limitation ([[PhoP]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/9988472 PubMed]
 +
** repressed by glucose ([[CcpA]]) {{PubMed|16825793}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 
** [[ResD]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/8631715,11222591 PubMed]
 
** [[ResD]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/8631715,11222591 PubMed]
** [[PhoP]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/9988472 PubMed]
+
** [[PhoP]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/9988472 PubMed]
 +
** [[CcpA]]: transcription repression {{PubMed|16825793}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''
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=References=
 
=References=
  
<pubmed>16885456,8631715,10094672,8682783,9352926,8631715,11222591,9988472, </pubmed>
+
<pubmed>16885456,8631715,10094672,8682783,9352926,8631715,11222591,9988472, 16825793</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 11:47, 28 December 2009

  • Description: two-component sensor kinase, regulation of aerobic and anaerobic respiration

Gene name resE
Synonyms ypxE
Essential no
Product two-component sensor kinase
Function regulation of aerobic and anaerobic respiration
MW, pI 66 kDa, 5.344
Gene length, protein length 1767 bp, 589 aa
Immediate neighbours sigX, resD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
ResE context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU23110

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of ResD
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: two transmembrane segments, C-terminal histidine phosphotransferase domain
  • Modification: autophosphorylation on a His residue
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed under anaerobic conditions (ResD) PubMed
    • expressed under conditions of phosphate limitation (PhoP) PubMed
    • repressed by glucose (CcpA) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References