Difference between revisions of "Two-component systems"
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* The ultimate target | * The ultimate target | ||
** [[Spo0A]] | ** [[Spo0A]] | ||
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| + | ==Related lists== | ||
| + | * [[phosphorelay]] | ||
| + | * [[response regulator aspartate phosphatases]] | ||
==Reviews== | ==Reviews== | ||
<pubmed>17338439 19575571 11406410 10966457 10932244 17158704 10094672 11489844 1664534 10745001 17913492 </pubmed> | <pubmed>17338439 19575571 11406410 10966457 10932244 17158704 10094672 11489844 1664534 10745001 17913492 </pubmed> | ||
Revision as of 20:32, 29 November 2009
Two component systems are signal transduction systems that consist of a sensor kinase and a response regulator (usually a transcription factor). The kinase autophosphorylates on a His residue (more preciely, one subunit of the dimeric kinase phosphorylates the His residue of the other subunit), and the phosphate group can then be transferred to an aspartate residue in the cognate response regulator. Some response regulators can also autophosphorylate using acety-phosphate as the phosphate donor. More complex signal transduction systems of this class are called phosphorelay. The paradigm for a phosphorelay is the pathway leading to the phosphorylation of Spo0A.
Contents
Two-component systems in B. subtilis (kinase, regulator)
- NarL-family
- OmpR family
The phosphorelay
- The ultimate target
Related lists
Reviews
