Difference between revisions of "PhrF"

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* '''Description:''' phosphatase (RapF) regulator <br/><br/>
+
* '''Description:''' phosphatase ([[RapF]]) regulator <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || phosphatase (RapF) regulator
+
|style="background:#ABCDEF;" align="center"| '''Product''' || phosphatase ([[RapF]]) regulator
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || control of sporulation initiation
+
|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[ComA]] activity
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 4 kDa, 10.237   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 4 kDa, 10.237   
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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:'''  
+
* '''Catalyzed reaction/ biological activity:''' binds to [[RapF]], this results in the inability of [[RapF]] to interact with [[ComA]] {{PubMed|15968044}}
  
 
* '''Protein family:''' phr family (according to Swiss-Prot)
 
* '''Protein family:''' phr family (according to Swiss-Prot)
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:'''
+
* '''Interactions:''' [[RapF]]-[[PhrF]] {{PubMed|15968044}}
  
 
* '''Localization:'''
 
* '''Localization:'''
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=References=
 
=References=
  
<pubmed>16816200,, </pubmed>
+
<pubmed>16816200,15968044, </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 08:17, 29 November 2009

  • Description: phosphatase (RapF) regulator

Gene name phrF
Synonyms ywhI
Essential no
Product phosphatase (RapF) regulator
Function control of ComA activity
MW, pI 4 kDa, 10.237
Gene length, protein length 117 bp, 39 aa
Immediate neighbours rapF, ywhH
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PhrF context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU37470

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: binds to RapF, this results in the inability of RapF to interact with ComA PubMed
  • Protein family: phr family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Jennifer M Auchtung, Catherine A Lee, Alan D Grossman
Modulation of the ComA-dependent quorum response in Bacillus subtilis by multiple Rap proteins and Phr peptides.
J Bacteriol: 2006, 188(14);5273-85
[PubMed:16816200] [WorldCat.org] [DOI] (P p)

Cristina Bongiorni, Shu Ishikawa, Sophie Stephenson, Naotake Ogasawara, Marta Perego
Synergistic regulation of competence development in Bacillus subtilis by two Rap-Phr systems.
J Bacteriol: 2005, 187(13);4353-61
[PubMed:15968044] [WorldCat.org] [DOI] (P p)