Difference between revisions of "GdpP"
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| − | * '''Description:''' | + | * '''Description:''' cyclic dinucleotide phosphodiesterase, involved in stress signaling and response <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || cyclic dinucleotide phosphodiesterase |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown | |style="background:#ABCDEF;" align="center"|'''Function''' || unknown | ||
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=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' cyclic dinucleotide phosphodiesterase, hydrolysis of di-cyclic AMP {{PubMed|19901023}} |
* '''Protein family:''' | * '''Protein family:''' | ||
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* '''Cofactor(s):''' | * '''Cofactor(s):''' | ||
| − | * '''Effectors of protein activity:''' | + | * '''Effectors of protein activity:''' ppGpp inhibits cyclic dinucleotide phosphodiesterase activity {{PubMed|19901023}} |
* '''Interactions:''' | * '''Interactions:''' | ||
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=References= | =References= | ||
| − | + | <pubmed> 19901023 </pubmed> | |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 09:04, 11 November 2009
- Description: cyclic dinucleotide phosphodiesterase, involved in stress signaling and response
| Gene name | yybT |
| Synonyms | |
| Essential | no |
| Product | cyclic dinucleotide phosphodiesterase |
| Function | unknown |
| MW, pI | 74 kDa, 4.865 |
| Gene length, protein length | 1977 bp, 659 aa |
| Immediate neighbours | rplI, yybS |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU40510
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: cyclic dinucleotide phosphodiesterase, hydrolysis of di-cyclic AMP PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity: ppGpp inhibits cyclic dinucleotide phosphodiesterase activity PubMed
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P37484
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Feng Rao, Rui Yin See, Dongwei Zhang, Delon Chengxu Toh, Qiang Ji, Zhao-Xun Liang
YybT is a signaling protein that contains a cyclic dinucleotide phosphodiesterase domain and a GGDEF domain with ATPase activity.
J Biol Chem: 2010, 285(1);473-82
[PubMed:19901023]
[WorldCat.org]
[DOI]
(I p)
