Difference between revisions of "FlgM"
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| − | * '''Description:''' anti-SigD, regulation of flagellin, motility, and chemotaxis <br/><br/> | + | * '''Description:''' anti-[[SigD]], regulation of flagellin, motility, and chemotaxis <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || anti-SigD | + | |style="background:#ABCDEF;" align="center"| '''Product''' || anti-[[SigD]] |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || control of SigD activity | + | |style="background:#ABCDEF;" align="center"|'''Function''' || control of [[SigD]] activity |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 9 kDa, 9.918 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 9 kDa, 9.918 | ||
| Line 93: | Line 93: | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** [[ScoC]]: transcription repression {{PubMed|19898538}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| Line 118: | Line 119: | ||
=References= | =References= | ||
| − | <pubmed>8955328,, </pubmed> | + | <pubmed>8955328,19898538 , </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 21:35, 10 November 2009
- Description: anti-SigD, regulation of flagellin, motility, and chemotaxis
| Gene name | flgM |
| Synonyms | |
| Essential | no |
| Product | anti-SigD |
| Function | control of SigD activity |
| MW, pI | 9 kDa, 9.918 |
| Gene length, protein length | 264 bp, 88 aa |
| Immediate neighbours | yvyG, yvyF |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU35430
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: flgM family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure:
- UniProt: P39809
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Prashant Kodgire, K Krishnamurthy Rao
A dual mode of regulation of flgM by ScoC in Bacillus subtilis.
Can J Microbiol: 2009, 55(8);983-9
[PubMed:19898538]
[WorldCat.org]
[DOI]
(I p)
K Fredrick, J D Helmann
FlgM is a primary regulator of sigmaD activity, and its absence restores motility to a sinR mutant.
J Bacteriol: 1996, 178(23);7010-3
[PubMed:8955328]
[WorldCat.org]
[DOI]
(P p)
