Difference between revisions of "GltX"
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− | * '''Description:''' glutamyl-tRNA synthetase <br/><br/> | + | * '''Description:''' glutamyl-tRNA synthetase, [[universally conserved protein]] <br/><br/> |
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=== Additional information=== | === Additional information=== | ||
− | + | [[universally conserved protein]] | |
=Expression and regulation= | =Expression and regulation= | ||
Revision as of 21:15, 4 November 2009
- Description: glutamyl-tRNA synthetase, universally conserved protein
Gene name | gltX |
Synonyms | |
Essential | yes PubMed |
Product | glutamyl-tRNA synthetase |
Function | translation |
Metabolic function and regulation of this protein in SubtiPathways: tRNA charging, Cys, Met & Sulfate assimilation | |
MW, pI | 55 kDa, 5.021 |
Gene length, protein length | 1449 bp, 483 aa |
Immediate neighbours | ispF, cysE |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU00920
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu) (according to Swiss-Prot)
- Protein family: class-I aminoacyl-tRNA synthetase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P22250
- KEGG entry: [3]
- E.C. number: 6.1.1.17
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information: the mRNA is very stable (half-life > 15 min) PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
G Hambraeus, C von Wachenfeldt, L Hederstedt
Genome-wide survey of mRNA half-lives in Bacillus subtilis identifies extremely stable mRNAs.
Mol Genet Genomics: 2003, 269(5);706-14
[PubMed:12884008]
[WorldCat.org]
[DOI]
(P p)