Difference between revisions of "BglH"
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* '''Operon:''' ''[[bglP]]-[[bglH]]-[[yxiE]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/7883710 PubMed] | * '''Operon:''' ''[[bglP]]-[[bglH]]-[[yxiE]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/7883710 PubMed] | ||
| − | * '''[[Sigma factor]]:''' [[SigA]] | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|7559347}} |
| − | * '''Regulation:''' repressed by glucose ([[CcpA]]) | + | * '''Regulation:''' |
| + | ** repressed by glucose ([[CcpA]], [[LicT]]) {{PubMed|7559347}} | ||
| + | ** induced by salicin ([[LicT]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/7883710 PubMed] | ||
| − | * '''Regulatory mechanism:''' [[CcpA]]: transcription repression, | + | * '''Regulatory mechanism:''' |
| + | ** [[CcpA]]: transcription repression, ([[CcpA]] binding site overlaps -35 region) {{PubMed|7559347}} | ||
| + | ** [[LicT]]-dependent [[RNA switch]] (antitermination, lack of [[LicT]]-dependent antitermination in the presence of gucose due to the requirement of [[LicT]] to be phosphorylated by [[PtsH| HPr]] {{PubMed|8626332}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
Revision as of 19:43, 31 October 2009
- Description: phospho-beta-glucosidase
| Gene name | bglH |
| Synonyms | |
| Essential | no |
| Product | phospho-beta-glucosidase |
| Function | salicin utilization |
| Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism | |
| MW, pI | 53 kDa, 4.957 |
| Gene length, protein length | 1407 bp, 469 aa |
| Immediate neighbours | yxiE, bglP |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU39260
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 6-phospho-beta-D-glucosyl-(1,4)-D-glucose + H2O = D-glucose + D-glucose 6-phosphate (according to Swiss-Prot)
- Protein family: glycosyl hydrolase 1 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P40740
- KEGG entry: [3]
- E.C. number: 3.2.1.86
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
