Difference between revisions of "GuaD"
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=Expression and regulation= | =Expression and regulation= | ||
− | * '''Operon:''' | + | * '''Operon:''' ''guaD'' {{PubMed|11101664}} |
− | * '''[[Sigma factor]]:''' [[SigB]] [http://www.ncbi.nlm.nih.gov/pubmed/15805528 PubMed] | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|11101664}}, [[SigB]] [http://www.ncbi.nlm.nih.gov/pubmed/15805528 PubMed] |
− | * '''Regulation:''' induced by stress ([[SigB]]) [http://www.ncbi.nlm.nih.gov/pubmed/15805528 PubMed] | + | * '''Regulation:''' |
+ | ** induced by stress ([[SigB]]) [http://www.ncbi.nlm.nih.gov/pubmed/15805528 PubMed] | ||
** induced in the presence of purine nucleotides (inducer: allantoin) ([[PucR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12029039 PubMed] | ** induced in the presence of purine nucleotides (inducer: allantoin) ([[PucR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12029039 PubMed] | ||
Revision as of 20:24, 1 October 2009
- Description: guanine deaminase, general stress protein
Gene name | guaD |
Synonyms | gde, yknA |
Essential | no |
Product | guanine deaminase |
Function | deamination of guanine to xanthine, purine salvage and interconversion |
Metabolic function and regulation of this protein in SubtiPathways: Purine salvage, Purine catabolism, Nucleotides (regulation) | |
MW, pI | 17 kDa, 4.999 |
Gene length, protein length | 468 bp, 156 aa |
Immediate neighbours | ohrB, metE |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU13170
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Guanine + H2O = xanthine + NH3 (according to Swiss-Prot)
- Protein family: cytidine and deoxycytidylate deaminase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure: 1WKQ
- UniProt: O34598
- KEGG entry: [3]
- E.C. number: 3.5.4.3
Additional information
Expression and regulation
- Operon: guaD PubMed
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References