Difference between revisions of "LcfB"
(→Expression and regulation) |
|||
| Line 90: | Line 90: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''lcfB'' {{PubMed|17189250}} |
| − | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|17189250}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** | + | ** induced in the presence of long-chain fatty acids ([[FadR]]) {{PubMed|17189250}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | ** [[FadR]]: transcription repression | + | ** [[FadR]]: transcription repression {{PubMed|17189250}} |
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 19:57, 16 September 2009
- Description: long-chain fatty-acid-CoA ligase
| Gene name | lcfB |
| Synonyms | yhfL |
| Essential | no |
| Product | long-chain fatty-acid-CoA ligase |
| Function | fatty acid degradation |
| MW, pI | 56 kDa, 5.301 |
| Gene length, protein length | 1539 bp, 513 aa |
| Immediate neighbours | yhfK, yhfM |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU10270
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA (according to Swiss-Prot)
- Protein family: ATP-dependent AMP-binding enzyme family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: O07610
- KEGG entry: [3]
- E.C. number: 6.2.1.3
Additional information
Expression and regulation
- Operon: lcfB PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
