Difference between revisions of "FolE2"

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(Expression and regulation)
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
+
* '''Operon:''' ''[[yciA]]-[[yciB]]-[[yciC]]'' {{PubMed|9811636}}
  
* '''[[Sigma factor]]:'''  
+
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|12426338}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
** induced by zinc starvation ([[Zur]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12426338 PubMed]
+
** induced by zinc starvation ([[Zur]]) {{PubMed|12426338}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
** [[Zur]]: transcription repression in  the presence of zinc [http://www.ncbi.nlm.nih.gov/sites/entrez/12426338 PubMed]
+
** [[Zur]]: transcription repression in  the presence of zinc {{PubMed|12426338}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''
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=References=
 
=References=
  
<pubmed>12426338,12426338,17032654</pubmed>
+
<pubmed>9811636 ,12426338,17032654</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 18:05, 19 August 2009

  • Description: type I GTP cyclohydrolase involved in zinc transport

Gene name yciA
Synonyms
Essential no
Product type I GTP cyclohydrolase
Function zinc uptake
MW, pI 34 kDa, 7.831
Gene length, protein length 915 bp, 305 aa
Immediate neighbours nasA, yciB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YciA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU03340

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate (according to Swiss-Prot)
  • Protein family: GTP cyclohydrolase IV family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
    • Zur: transcription repression in the presence of zinc PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References