DltE

• Description: D-alanine transfer from undecaprenol-phosphate to the poly(glycerophosphate) chain
  
  

Gene name	dltE
Synonyms	ipa-1r
Essential	no
Product	D-alanine transfer from undecaprenol-phosphate to the poly(glycerophosphate) chain
Function	biosynthesis of teichoic acid
MW, pI	28 kDa, 5.095
Gene length, protein length	756 bp, 252 aa
Immediate neighbours	dltD, ywaA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU38540

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: short-chain dehydrogenases/reductases (SDR) family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P39577

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: dltA-dltB-dltC-dltD-dltE

• Sigma factor: SigD, SigX

• Regulation:
  • RelA dependent downregulation (Class I) during stringent response PubMed
  • repressed under conditions that trigger sporulation (Spo0A) PubMed

• Regulatory mechanism: activated by YvrHb PubMed
  • Spo0A: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: