Difference between revisions of "QoxD"

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* '''Regulation:'''  
 
* '''Regulation:'''  
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** [[RelA]] dependent downregulation (Class I) during stringent response {{PubMed|11948165}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  

Revision as of 16:23, 31 July 2009

  • Description: cytochrome aa3 quinol oxidase (subunit IV)

Gene name qoxD
Synonyms ipa-40d
Essential no
Product cytochrome aa3 quinol oxidase (subunit IV)
Function respiration
MW, pI 13 kDa, 5.942
Gene length, protein length 372 bp, 124 aa
Immediate neighbours ywcE, qoxC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
QoxD context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU38140

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Ubiquinol-8 + O2 = Ubiquinone-8 + H2O (according to Swiss-Prot)
  • Protein family: cytochrome c oxidase bacterial subunit 4 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

N Azarkina, S Siletsky, V Borisov, C von Wachenfeldt, L Hederstedt, A A Konstantinov
A cytochrome bb'-type quinol oxidase in Bacillus subtilis strain 168.
J Biol Chem: 1999, 274(46);32810-7
[PubMed:10551842] [WorldCat.org] [DOI] (P p)