Difference between revisions of "RplK"

From SubtiWiki
Jump to: navigation, search
Line 94: Line 94:
 
* '''Sigma factor:'''  
 
* '''Sigma factor:'''  
  
* '''Regulation:''  
+
* '''Regulation:'''
 +
** [[RelA]] dependent downregulation (Class I) during stringent response {{PubMed|11948165}}
 
** [[RelA]] dependent downregulation (Class I) during stringent response {{PubMed|11948165}}
 
** [[RelA]] dependent downregulation (Class I) during stringent response {{PubMed|11948165}}
  

Revision as of 16:15, 31 July 2009

  • Description: ribosomal protein

Gene name rplK
Synonyms relC, tsp
Essential no
Product ribosomal protein L11 (BL11)
Function translation
MW, pI 14 kDa, 9.718
Gene length, protein length 423 bp, 141 aa
Immediate neighbours nusG, rplA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RplK context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU01020

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: ribosomal protein L11P family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 1FOX (C-terminal domain, Geobacillus stearothermophilus), 2FOW (RNA binding domain in complex with RNA, Geobacillus stearothermophilus)
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

S Zhang, J M Scott, W G Haldenwang
Loss of ribosomal protein L11 blocks stress activation of the Bacillus subtilis transcription factor sigma(B).
J Bacteriol: 2001, 183(7);2316-21
[PubMed:11244072] [WorldCat.org] [DOI] (P p)