PrpE

• Description: protein tyrosine phosphatase
  
  

Gene name	prpE
Synonyms	yjbP
Essential	no
Product	protein tyrosine phosphatase
Function	unknown
MW, pI	27 kDa, 6.747
Gene length, protein length	732 bp, 244 aa
Immediate neighbours	yjbO, yjbQ
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU11630

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: P₁,P(4)-bis(5'-guanosyl) tetraphosphate + H₂O = GTP + GMP (according to Swiss-Prot)

• Protein family: prpE family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: forespore (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O31614

• KEGG entry: [2]

• E.C. number: 3.6.1.17

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Krzysztof Hinc, Krzysztofa Nagórska, Adam Iwanicki, Grzegorz Wegrzyn, Simone J Séror, Michal Obuchowski
Expression of genes coding for GerA and GerK spore germination receptors is dependent on the protein phosphatase PrpE.
J Bacteriol: 2006, 188(12);4373-83
[PubMed:16740944] [WorldCat.org] [DOI] (P p)

Adam Iwanicki, Anna Herman-Antosiewicz, Marcin Pierechod, Simone J Séror, Michał Obuchowski
PrpE, a PPP protein phosphatase from Bacillus subtilis with unusual substrate specificity.
Biochem J: 2002, 366(Pt 3);929-36
[PubMed:12059787] [WorldCat.org] [DOI] (P p)