Difference between revisions of "DacC"
| Line 78: | Line 78: | ||
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1W5D 1W5D], [http://www.rcsb.org/pdb/explore.do?structureId=2J9P 2J9P] (complex with a peptidoglycan mimetic peptide) | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1W5D 1W5D], [http://www.rcsb.org/pdb/explore.do?structureId=2J9P 2J9P] (complex with a peptidoglycan mimetic peptide) | ||
| − | * ''' | + | * '''UniProt:''' [http://www.uniprot.org/uniprot/P39844 P39844] |
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU18350] | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU18350] | ||
Revision as of 13:00, 20 July 2009
- Description: penicillin-binding protein 4A, D-alanyl-D-alanine carboxypeptidase
| Gene name | dacC |
| Synonyms | pbp |
| Essential | no |
| Product | penicillin-binding protein 4A, D-alanyl-D-alanine carboxypeptidase |
| Function | carboxypeptidase |
| MW, pI | 52 kDa, 5.413 |
| Gene length, protein length | 1473 bp, 491 aa |
| Immediate neighbours | ppsA, yoxA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU18350
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Preferential cleavage: (Ac)(2)-L-Lys-D-Ala-|-D-Ala (according to Swiss-Prot)
- Protein family: ATP-dependent AMP-binding enzyme family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- UniProt: P39844
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Dirk-Jan Scheffers, Laura J F Jones, Jeffery Errington
Several distinct localization patterns for penicillin-binding proteins in Bacillus subtilis.
Mol Microbiol: 2004, 51(3);749-64
[PubMed:14731276]
[WorldCat.org]
[DOI]
(P p)
D L Popham, M E Gilmore, P Setlow
Roles of low-molecular-weight penicillin-binding proteins in Bacillus subtilis spore peptidoglycan synthesis and spore properties.
J Bacteriol: 1999, 181(1);126-32
[PubMed:9864321]
[WorldCat.org]
[DOI]
(P p)
L B Pedersen, T Murray, D L Popham, P Setlow
Characterization of dacC, which encodes a new low-molecular-weight penicillin-binding protein in Bacillus subtilis.
J Bacteriol: 1998, 180(18);4967-73
[PubMed:9733705]
[WorldCat.org]
[DOI]
(P p)
